SUPPORTIVE & PALLIATIVE CARE FOR PULMONARY ARTERIAL HYPERTENSION
Pulmonary Hypertension is elevated blood pressure in the pulmonary artery averaging 25 mm Hg or above at rest. Elevated pulmonary artery pressure can be caused by abnormalities in the precapillary pulmonary arterioles called pulmonary arterial hypertension(PAH) .
It is a high blood pressure that affects the arteries
in lungs and right side of your heart. In PAH blood vessels in lungs are narrowed, blocked
or destroyed .So PAH patients are cared by a multidisciplinary team who are
able to implement both pharmacological therapy and supportive therapy &
palliative care.
Supportive Therapy includes:-
·
Oxygen
Therapy
·
Diuretics
·
Anticoagulants
·
Cardiovascular
Medications
·
Exercise
·
Therapy
for Arrhythmias and Anaemia
Decisions
regarding starting each of these therapies should be made on a patient to
patient basis in the appropriate clinical scenario.
Palliative Care is broadly
categorised into:-
1)
Invasive
2)
Non-Invasive
Invasive Modalities includes:-
·
Atrial Septostomy
Ø Is a percutaneous procedure by which
a right to left shunt is created in the atrial septum allowing decompression of
the right side of the heart.
Ø Atrial Septostomy may improve
symptoms, haemodynamics and potentially survival in patients.
Ø Improvement in functional class, 6-
min walking distance and haemodynamic parametes such as cardiac index and right
ventricular pressure following atrial septostomy in PAH patients has been
reported.
·
Right Ventricular Assist Devices
Ø The placement of a right ventricular
assist device (RVAD).
Ø Evaluation of RVAD flow rate on
haemodynamic measures was done. With increasing RVAD speed there was an
increase in total pulmonary blood flow, mean pulmonary artery pressure,left
ventricular filling pressure and cardiac output as wellas a decrease in right
atrial preesure.
·
Pulmonary Artery Denervation
Ø It involves radiofrequency ablation
of sympathetic nerve fibres located at the level of the main pulmonary artery bifurcation.
Ø The improvement in haemodynamics and
functional capacity shows that PADN might be a promising palliative procedure.
Non-Invasive Interventions include:-
·
Pain
control
·
Management
of nausea, shortness of breath and anorexia
·
Screening
for depression & anxiety
·
Counselling
if needed
·
Educating
patients about their condition
·
Providing
financial assistance/
Information on health insurance coverage
·
Encouraging
patients to join support group
Patients with PAH and their families experience physical, emotional,
social and spiritual distress. With both opioid and non-opioid based therapies
, palliative medicine physicians can work with patients towards the goal of
living with less pain. Counselling helps patients develop coping skills and
reach peace with their new state.
The
components of palliative care team are:-
·
Doctors
·
Nurses
·
Family
Support
·
Care
providers
·
Social
workers
·
Pastoral
care workers
By implementing these approaches, patient
management can be optimised to ensure the best possible outcome for all
patients with PAH .Pulmonary Arterial Hypertension remains a fatal disease.
Efforts to slow down disease progression are essential and research is ongoing
to develop therapies with novel modes of action.
Dr. Nividha Chhabra

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